Publications

(2015 ~ 현재)

2024

Document

Glutaminase-1 Inhibition Alleviates Senescence of Wharton’s Jelly-derived Mesenchymal Stem Cells via Senolysis

Stem Cells Translational Medicine

Lee EJ, Kim SJ, Jeon SY, Chung SB, Park SE, Kim JS, Choi SJ, Oh SY, Ryu GH, Jeon HB, Chang JW

2024

Document

(Review) Manufacturing Cell and Gene Therapies: Challenges in Clinical Translation

Annals of Laboratory Medicine

Lee NK, Chang JW

2023

Document

Nervonic Acid Inhibits Replicative Senescence of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells

International Journal of Stem Cells

Kim SJ, Kwon SJ, Chung SB, Lee EJ, Park SE, Choi SJ, Oh SY, Ryu GH, Jeon HB, Chang JW

2023

Document

Iron Oxide Nanoparticle-Incorporated Mesenchymal Stem Cells for Alzheimer's Disease Treatment

Nano Letters

Jung MG, Kim HS, Hwang JW, Choi YJ, Kang MK, Kim CS, Hong JH, Lee NK, Moon SJ, Chang JW, Choi SJ, Oh SY, Jang HM,

Na DL, Kim BS

2022

Document

A New Method of Myostatin Inhibition in Mice via Oral Administration of Lactobacillus casei Expressing Modified Myostatin Protein, BLS-M22

International Journal of Molecular Sciences

Sung DK, Kim HS, Park SE, Lee JW,Kim JA, Park YC, Jeon HB, Chang JW, Lee JH

2022

Document

Combination of Dexamethasone and Tofacitinib Reduces Xenogeneic MSC-Induced Immune Responses in a Mouse Model of Alzheimer's Disease

Biomedicines

Lee NK, Myeong SH, Hwang JW, Sa JK, Son HJ, Kim HJ, Jang HM, Chang JW, Na DL

2022

Document

Wharton’s Jelly-Derived Mesenchymal Stem Cells with High Aurora Kinase A Expression Show Improved Proliferation, Migration, and Therapeutic Potential

Stem Cells International

Kim SJ, Park SE, Jeong JB, Oh SJ, Choi A, Kim YH, Choi SJ, Oh SY, Ryu GH, Jeon HB, Chang JW

2021

Document

Wharton’s Jelly-Derived Mesenchymal Stem Cells Reduce Fibrosis in a Mouse Model of Duchenne Muscular Dystrophy by Upregulating MicroRNA 499

Biomedicines

Park SE, Jeong JB, Oh SJ, Kim SJ, Kim HS, Choi A, Choi SJ, Oh SY, Ryu GH, Lee JH, Jeon HB, Chang JW

2021

Document

Immunosuppressant Drugs Mitigate Immune Responses Generated by Human Mesenchymal Stem Cells Transplanted into the Mouse Parenchyma

Cell Transplantation

Hwang JW, Myeong SH, Lee NH, Kim HS, Son HJ, Chang JW, Lee NK, Na DL

2021

Document

Exposure of Mesenchymal Stem Cells to an Alzheimer’s Disease Environment Enhances Therapeutic Effects

Stem Cells International

Park SE, Kim HS, Kwon SJ, Kim MJ, Choi SJ, Oh SY, Ryu GH, Jeon HB, Na DL, Chang JW

2021

Document

Intraspinal Cavity Injection of Human Mesenchymal Stem Cells and Tracking their Migration into the Rat Brain

JoVE

Kim HS, Lee S, Chang JW, Kim AR, Jang H, Na DL

2021

Document

Comparative Proteomic Analysis of the Mesenchymal Stem Cells Secretome from Adipose, Bone Marrow, Placenta and Wharton's Jelly

International Journal of Molecular Sciences

Shin SH, Lee JM, Kwon YM, Park KS, Jeong JH, Choi SJ, Bang SI, Chang JW, Lee CJ

2020

Document

Fibulin 5, a human Wharton's jelly‐derived mesenchymal stem cells‐secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin‐RAC1 signaling axis

STEM CELLS

Won SY, Kwon SJ, Jeong HS, Chung KW, Choi BO, Chang JW, Lee JE

2020

Document

Pressure Stimuli Improve the Proliferation of Wharton's Jelly-Derived Mesenchymal Stem Cells under Hypoxic Culture Conditions

International Journal of Molecular Sciences

Park SE, Kim HS, Kwon SJ, Choi SJ, Oh SY, Ryu GH, Jeon HB, Chang JW

2020

Document

Ethionamide Preconditioning Enhances the Proliferation and Migration of Human Wharton's Jelly-Derived Mesenchymal Stem Cells

International Journal of Molecular Sciences

Lee NH, Myeong SH, Son HJ, Hwang JW, Lee NK, Chang JW, Na DL

2020

Document

Anti-Fibrotic Effect of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells on Skeletal Muscle Cells, Mediated by Secretion of MMP-1

International Journal of Molecular Sciences

Choi A, Park SE, Jeong JB, Choi SJ, Oh SY, Ryu GH, Lee JH, Jeon HB, Chang JW

2020

Document

Exploring the Potential of Mesenchymal Stem Cell-Based Therapy in Mouse Models of Vascular Cognitive Impairment

International Journal of Molecular Sciences

Lee NK, Kim HS, Chang JW, Jang HM, Kim HN, Yang JH, Kim JY, Son JP, Na DL

2020

Document

A Comparison of Immune Responses Exerted Following Syngeneic, Allogeneic, and Xenogeneic Transplantation of Mesenchymal Stem Cells into the Mouse Brain

International Journal of Molecular Sciences

Hwang JW, Lee NK, Yang J, Son HJ, Bang SI, Chang JW, Na DL

2020

Document

Recovery of Tendon Characteristics by Inhibition of Aberrant Differentiation of Tendon Derived Stem Cells from Degenerative Tendinopathy

International Journal of Molecular Sciences

Kim SJ, Oh HW, Chang JW, Kim SJ

2019

Document

Cerebrospinal fluid from Alzheimer’s disease patients as an optimal formulation for therapeutic application of mesenchymal stem cells in Alzheimer’s disease

Scientific Reports

Lee J, Kwon SJ, Kim JH, Jang H, Lee NK, Hwang JW, Kim JH, Chang JW, Na DL

2018

Document

(Review) Killing two birds with one stone: The multifunctional roles of mesenchymal stem cells in the treatment of neurodegenerative and muscle diseases

Histology and Histopathology

Lee NK, Na DL, Chang JW

2018

Document

(Review) Optimal mesenchymal stem cell delivery routes to enhance neurogenesis for the treatment of Alzheimer's disease: optimal MSCs delivery routes for the treatment of AD

Histology and Histopathology

Park SE, Lee NK, Na DL, Chang JW

2017

Document

Lowering the concentration affects the migration and viability of intracerebroventricular-delivered human mesenchymal stem cells

Biochemical and Biophysical Research Communications

Kim HS, Lee NK, Yoo D, Lee J, Choi SJ, Oh W, Chang JW, Na DL

2017

Document

Agouti Related Peptide Secreted Via Human Mesenchymal Stem Cells Upregulates Proteasome Activity in an Alzheimer's Disease Model

Scientific Reports

Lee NK, Park SE, Kwon SJ, Shim S, Byeon Y, Kim JH, Na DL, Chang JW

2017

Document

Magnetic Resonance Imaging of Ferumoxytol-Labeled Human Mesenchymal Stem Cells in the Mouse Brain

Stem Cell Reviews and Reports

Lee NK, Kim HS, Yoo D, Hwang JW, Choi SJ, Oh W, Chang JW, Na DL

2016

Document

Distribution of human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) in canines after intracerebroventricular injection

Neurobiology of Aging

Park SE, Jung NY, Lee NK, Lee J, Myeong SH, Kim HS, Suh YL, Lee JI, Cho KR, Chang JW, Na DL

2016

Document

Inhibition of never in mitosis A (NIMA)-related kinase-4 reduces survivin expression and sensitizes cancer cells to TRAIL-induced cell death

Oncotarget.

Park SJ, Jo DS, Jo SY, Shin DW, Shim S, Jo YK, Shin JH, Ha YJ, Chang JW, Kim JC, Cho DH

2016

Document

Activin A secreted by human mesenchymal stem cells induces neuronal development and neurite outgrowth in an in vitro model of Alzheimer's disease: neurogenesis induced by MSCs via activin A

Archives of Pharmacal Research

Park SE, Lee J, Chang EH, Kim JH, Sung JH, Na DL, Chang JW

2016

Document

Anti-apoptotic Effects of Human Wharton's Jelly-derived Mesenchymal Stem Cells on Skeletal Muscle Cells Mediated via Secretion of XCL1

Molecular Therapy

Kwon S, Ki SM, Park SE, Kim MJ, Hyung B, Lee NK, Shim S, Choi BO, Na DL, Lee JE, Chang JW

2016

Document

Intra-Arterially Delivered Mesenchymal Stem Cells Are Not Detected in the Brain Parenchyma in an Alzheimer's Disease Mouse Model

PLoS One

Lee NK, Yang J, Chang EH, Park SE, Lee J, Choi SJ, Oh W, Chang JW, Na DL

2016

Document

Distribution of human umbilical cord blood-derived mesenchymal stem cells in the Alzheimer's disease transgenic mouse after a single intravenous injection.

Neuroreport

Park SE, Lee NK, Lee J, Hwang JW, Choi SJ, Hwang H, Hyung B, Chang JW, Na DL

2015

Document

GDF-15 secreted from human umbilical cord blood mesenchymal stem cells delivered through the cerebrospinal fluid promotes hippocampal neurogenesis and synaptic activity in an Alzheimer's disease model

Stem Cells and Development

Kim DH, Lee D, Chang EH, Kim JH, Kyung JW, Kim SH, Oh JS, Shim SM,Na DL, Oh W, Chang JW

2015

Document

Inhibition of autophagy suppresses sertraline-mediated primary ciliogenesis in retinal pigment epithelium cells

PLoS One

Kim ES, Shin JH, Park SJ, Jo YK, Kim JS, Kang IH, Nam JB, Chung DY, Lee EH, Chang JW, Cho DH